CURRENT Suspension Bioreactor Series

Discovery of a Novel O₂ Transfer Method

Jia Q. et al., A Bioreactor System Based on a Novel Oxygen Transfer Method, BioProcess International, pgs. 66-70, 78; June 2008.

Hui M, A Method to Increase Dissolved Oxygen in a Culture Vessel, WO 2007/142664.

Application of a Novel O₂ Transfer Method - CURRENT Bioreactor Series for Suspension Culture


5L Bioreactor Bag	50L Bioreactor Bag

Features:

Effective O₂ transfer to support extremely high-density cell culture
No sparging - no bubble-burst related cell death
No impellor - no shear-force related cell damage
Single-use system - no production down-time
Incredibly reliable system for suspension cell culture that requires no process development to achieve successful cell cultures.
All models (5L, 50L & 150L) are equipped with perfusion device.
Affordably priced

"Current" Suspension Bioreactor Cell Culture Data

5L "Current" Suspension Bioreactor

Cell line name	Culture mode	Cell density	Optimized or not?
CHO-S	Fed-batch	2.0 X 10⁷cells/ml	none
CHO-K1	Fed-batch	1.5 X 10⁷cells/ml	none
SF9 (insect)	Batch	1.8 X 10⁷cells/ml	none

50L "Current" Suspension Bioreactor

Cell line name	Culture mode	Cell density	Optimized or not?
CHO-S	Fed-batch	2.5 X 10⁷cells/ml	none
CHO-K1	Fed-batch	2.0 X 10⁷cells/ml	none
SF9 (insect)	Batch	pending	none

150L "Current" suspension bioreactor

Cell line name	Culture mode	Cell density	Optimized or not?
CHO-S	Fed-batch	1.8 X 10⁷cells/ml	none
CHO-K1	Fed-batch	1.4 X 10⁷cells/ml	none
SF9 (insect)	Batch	pending	none

CURRENT Bioreactor as a DO Generator

CURRENT Bioreactor series are used here as a DO generator and all have their own affiliated perfusion columns ready-to-use as an alternative to suspension cell culture for attached cell culture as a perfusion system. (Refer to Perfusion Bioreactor Series Section)

For further information regarding the CURRENT Bioreactor for suspension cell culture please contact info@amprotein.com.